Liverpool will kick off their Premier League title defence with a home game against Bournemouth on Friday, August 15.
Arne Slot’s side have the chance to secure the first points of the new season at Anfield as they launch the 2025-26 campaign.
Thomas Frank’s first match as Tottenham boss will come the following day at home against newly-promoted Burnley, while Sunderland’s return to the top flight also begins at home on August 16 against West Ham.
The third newcomers, Leeds, have been given the Monday night slot for a clash with Everton at Elland Road.
Other fixtures on the opening weekend see Aston Villa face Newcastle at Villa Park in the early kick-off on the Saturday, while Manchester City travel to Wolves later the same day.
Ruben Amorim’s Manchester United have been handed an immediate challenging test with a home game against Arsenal on Sunday, August 17.
Everton’s first Premier League match at their new Hill Dickinson Stadium comes the following weekend against Brighton, while notable fixtures that weekend include Arsenal hosting Leeds, Tottenham travelling to Manchester City and Liverpool visiting Newcastle.
It could be a testing start for Slot’s champions, with a home game against Arsenal on the third weekend ahead of the first international break of the new term.
The first Manchester derby of the campaign comes immediately after the break, on the weekend of September 13 at the Etihad Stadium, where Pep Guardiola’s new-look team will hope to stamp their authority after a difficult season.
A probable key couple of weeks for City concludes with a trip to Arsenal the following weekend, while the weekend of September 20 also sees the Merseyside derby take place at Anfield and a meeting between Manchester United and Chelsea.
Burnley appear to have the most tricky start of the promoted sides, with Spurs, Manchester United, Liverpool, Nottingham Forest, Manchester City and Aston Villa all among their first eight fixtures, while they also face clashes with Leeds and Sunderland.
The weekend of October 18 will be immediately marked in the diaries of Manchester United and Liverpool fans, with the rivals clashing at Anfield.
The first meeting between Manchester City and Liverpool comes the weekend of November 8 at the Etihad Stadium, with the first north London derby between Arsenal and Tottenham taking place the other side of the international break at the Emirates.
The north-east derby, meanwhile, returns to the Premier League the weekend of December 13 when Newcastle make the short trip to Sunderland’s Stadium of Light.
The first weekend of the new year will see matches between Leeds and Manchester United and Manchester City and Chelsea, with Arsenal facing Liverpool the following midweek.
Notable fixtures in the second half of the season include the second Manchester derby at Old Trafford the weekend of January 17, while Liverpool host Manchester City the weekend of February 7.
Everton fans will have to wait until the weekend of April 18 for the first Merseyside derby at their new home, with Arsenal also travelling to Manchester City in that round of fixtures.
The final day of the season falls on Sunday, May 24, with matches including Manchester City against Aston Villa.
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