Liverpool captain Jordan Henderson is suspended for the 232nd Merseyside derby.
The England international serves a one-match ban for his red card at Watford last weekend, while fellow midfielder Adam Lallana returned to training on Thursday.
Xherdan Shaqiri or Naby Keita are likely to come into the side in Henderson's place.
Meanwhile, Trent Alexander-Arnold is expected to return at right-back after being rested against Paris St Germain in midweek.
Provisional squad: Alisson, Alexander-Arnold, Van Dijk, Gomez, Robertson, Milner, Wijnaldum, Keita, Salah, Firmino, Mane, Mignolet, Lovren, Moreno, Fabinho, Lallana, Shaqiri, Sturridge.
