Jurgen Klopp opted against resting his key men for the visit of Newcastle as Mohamed Salah, Sadio Mane and Roberto Firmino led a strong side at Anfield.
Trent Alexander-Arnold returned for Liverpool as they set about maintaining their four-point lead at the top of the pile.
Fabinho, Naby Keita and James Milner dropped out, with Georginio Wijnaldum and Xherdan Shaqiri coming into the midfield for Klopp's men
Team news
Liverpool XI: Alisson, Alexander-Arnold, Lovren, Van Dijk, Robertson, Henderson, Wijnaldum, Shaqiri, Salah, Mane, Firmino
Klopp insists no-one can feel safe in the Premier League title race - even with a four-point lead at Christmas.
Klopp's unbeaten side top the table with Manchester City in second and Tottenham six points off the pace in third.
But the German knows nothing can be taken for granted, especially after watching Spurs' 6-2 demolition of Everton on Sunday.
"You (the media) make these stories about who is in and who is out," said Klopp.
"I saw the game against Everton who played absolutely more than OK and then they (Spurs) hit pretty much everything and it was really impressive how Tottenham did.
"The same will happen to Arsenal and Chelsea. No decision is made, why should it be? Nobody should feel safe, no-one should feel out of the race. It is not a time to think about it.
"For me they (Tottenham) were never out so why should people be surprised they are now in? A lot of teams are in whatever you call the title race and that is how it should be.
"That is maybe only the difference to last year when pretty much nobody was in any more at this time and that is good for all supporters out there.
"Being unbeaten in the league until December is not something I had too often in my life. We did really well so far, and we have to do even better from now on. That's the challenge for us."
