Xherdan Shaqiri makes his first start of the season as Jurgen Klopp rings the changes for the visit of Everton at Anfield.
The Switzerland international has been restricted to just three substitute appearances totaling 15 minutes so far for Liverpool this term but is handed a second successive start at Anfield in the Merseyside derby.
Mohamed Salah and Roberto Firmino are among those rested with Divock Origi and Sadio Mane completing the front three for Klopp's Premier League leaders.
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The midfield trio is Adam Lallana, Gini Wijnaldum and James who captains the side in the absence of the rested Jordan Henderson.
Adrian deputises for the suspended Alisson with Trent Alexander-Arnold, Dejan Lovren, Virgil van Dijk and Andy Robertson completing the XI.
Liverpool: Adrian; Alexander-Arnold, Lovren, Van Dijk, Robertson; Milner, Lallana, Wijnaldum; Shaqiri, Origi, Mane
Subs: Kelleher, Gomez, Keita, Henderson, Oxlade-Chamberlain, Salah, Firmino.
