Ozan Kabak misses out through injury for Liverpool as Rhys Williams starts against Southampton at centre-back.
Williams makes his first start since the 1-0 defeat to Fulham two months ago as he partners Nat Phillips at the back for the Reds.
Kabak, who is described as a "minor injury concern", joins Ben Davies on a lengthy Liverpool injury list at centre-back that also includes long-term absentees Virgil van Dijk, Joe Gomez and Joel Matip.
In midfield, Thiago Alcantara and Gini Wijnaldum will supplement Fabinho at the base as Jurgen Klopp names a strong-looking engine room for the visit of the Saints.
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Up front, Sadio Mane and Mohamed Salah will flank Diogo Jota as Roberto Firmino drops to the bench.
Liverpool: Alisson; Alexander-Arnold, R. Williams, Phillips, Robertson; Fabinho, Wijnaldum, Thiago; Salah, Mane, Jota.
Subs: Adrian, Firmino, Oxlade-Chamberlain, Jones, Tsimikas, Shaqiri, Woodburn, N Williams, Koumetio.
