Napoli star Lorenzo Insigne has been ruled out of their Champions League clash with Liverpool .
Jurgen Klopp's side welcome Napoli to Anfield on Wednesday night in their penultimate Group H clash.
Insigne, 28, played over an hour in the 1-1 draw with AC Milan this weekend before picking up an elbow injury.
And the Serie A side have confirmed he will play no part in the clash at Anfield.
Napoli have been able to include Fabian Ruiz and Faouzi Ghoulam in their squad for the encounter, despite both missing training on Monday.
Liverpool sit top of the group going into the clash, one point ahead of Napoli, despite losing in Italy earlier this season.
Napoli boss Carlo Ancelotti makes his return to England, amid recent speculation linking him with the Tottenham job.
The former Chelsea chief was reportedly a contender to replace Mauricio Pochettino, before Jose Mourinho was appointed.
But Spurs accepted they could not afford the Italian, who also finds himself under pressure.
Napoli sit seventh in Serie A and have managed just five wins from their first 13 encounters.
Saturday's draw with Milan made it six matches without a win in all competitions for the Serie A side.
Dries Mertens and Hirving Lozano are expected to fill the void left by the injured Insigne, while Fernando Llorente is another option.
