Liverpool's reign as Champions League holders is over after Atletico Madrid won 3-2 at Anfield to reach the quarter-finals of the competition.
Atletico headed into the second leg of this last-16 tie with a 1-0 advantage courtesy of their win in Madrid, but Georginio Wijnaldum's first-half header sent the sides in level 1-1 on aggregate with 45 minutes left to play.
Jan Oblak was in superb form with save after save to deny Jurgen Klopp's Liverpool, and the game went into extra-time.
Roberto Firmino put Liverpool in front four minutes into extra-time, but a big call from Diego Simeone was to prove drastic.
Simeone took off Diego Costa 55 minutes in, prompting a furious reaction from the former Chelsea striker. His replacement, however, made the difference - Marcos Llorente cancelled out Firmino's strike in the seventh minute of extra-time to put Atletico ahead on away goals following an error from Adrian.
Llorente then struck on the stroke of half-time in extra-time to leave Liverpool needing two goals to progress, but another Simeone sub - Alvaro Morata - scored with seconds left to seal a 4-2 aggregate win and end Liverpool's Champions League defence.
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