Ibrahima Konate comes in for Virgil van Dijk at centre-back as Liverpool entertain Newcastle United at Anfield.
Van Dijk is one of three players to have returned a suspected positive COVID-19 test as Fabinho also misses out for the same reason with Alex Oxlade-Chamberlain replacing the Brazilian.
Curtis Jones is the third player to have returned a positive test and all three are now set to self-isolate.
Jones has only returned to first-team training this week after an eye injury but will play no part as the Reds aim to close the gap on Manchester City at the top of the Premier League to just one point.
Liverpool vs Newcastle United LIVE - score and stream from Anfield
The remainder of Jurgen Klopp’s senior set-up – including the first-team squad and coaching staff – were all re-tested on Thursday with everyone receiving a negative result.
Mohamed Salah, Diogo Jota and Sadio Mane make up the front three with Roberto Firmino only given a place on the bench for the visit of the Magpies.
Liverpool: Alisson; Alexander-Arnold, Matip, Konate, Robertson; Henderson, Thiago, Oxlade-Chamberlain; Salah, Jota, Mane.
Subs: Kelleher, Pitaluga, Milner, Keita, Firmino, Gomez, Minamino, Tsimikas, Williams.
