La Liga chief Javier Tebas fears Barcelona, Real Madrid and Juventus are 'plotting' a revised European Super League.
The initial plans in April, which included the 'big six' Premier League clubs, failed after English clubs withdrew amid fan protests.
Liverpool captain Jordan Henderson led the player's response to the proposals and Jurgen Klopp said the only positive thing to take from the plans was that they 'didn't happen'.
While the Premier League clubs all ended their involvement, Tebas says a Super League could still happen without them.
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Speaking to Marca, he said: "The three castaways [Barcelona, Real Madrid and Juventus] who remain with the flag are talking and I can tell you ahead: they already know that the English are not going to be there.
"Now they are setting up a kind of Super League with the rest of the leagues so that the enemy is not only the Champions League, but also the Premier.
"The Super League that we saw in April worries me zero, but the concept does. They think that in football the big clubs have to rule...there is a lot of selfishness there.
"It is true that they are big, but where have they become big? Competing against Osasuna, Betis...and they can't put them aside now.
"It would mean, to the Spanish League, lose about €1.2billion. The leagues are united, even the Premier."
Real Madrid president Florentino Perez promised to revive the plans after they collapsed earlier this year, insisting the Super League 'still exists'.
"If anyone thinks the Super League is dead, are they wrong? Absolutely," he said back in April.
"We're going to keep working and what everyone thinks is for the best will emerge. The project is on standby.
"The Super League still exists."