Jo Swinson is on course to lose her seat to the SNP, the general election exit poll suggests.
The survey gives the Liberal Democrat leader just a 5 per cent chance of retaining the Dunbartonshire East seat.
Ms Swinson won the constituency by a margin of 5,339 votes in 2017 but it has been a top target for the SNP this time around.
Even if she holds on, she is likely to face calls to resign as party leader, with the exit poll predicting a disappointing night for the Liberal Democrats. The party is on course to win just 15 seats.
A potential surprise victory for Luciana Berger in Finchley and Golders Green would appear to provide the only glimmer of hope for the Lib Dems.
However, the Liberal Democrats' House of Lords leader, Lord Newby, insisted that the result was not a disaster for his party.
He told Sky News: “Our vote share will have gone up, the number of seats will have gone up. Our view at the moment is that the position in Scotland for us is rather betterthan the poll suggests.
“Like everybody, we want a lot more votes and a lot more seats. We’re going to get some more votes and some more seats, at a time when the other party that’s been arguing on a Remain platform has completely collapsed. We have not completely collapsed – we’ve moved forward not as much as we’d wanted, by a very long way.”
Asked about the prospect of Ms Swinson losing her seat, he said: “All I’m hearing from Scotland is that the reaction we found on the doorsteps suggests that the exit poll is rather optimistic for the SNP.”
The poll suggested that the SNP is on course to increase its number of seats from 35 to 55.
Nicola Sturgeon, the SNP leader, tweeted: “Exit poll suggests good night for the SNP – but it is just an exit poll and there are many marginals, so let’s just wait and see. What it indicates UK wide though is grim.”