Scotland Yard has launched a murder investigation after a 52-year-old man died following being hit by a car.
The incident, in Leytonstone's High Road, happened in the early hours of Sunday.
Two men were hit by the vehicle in east London, the force said.
The 52-year-old died in hospital at 5.18pm on Sunday.
A 32-year-old remains in hospital with serious but non life-threatening injuries.
Detective Chief Inspector Mark Wrigley, leading the investigation, said: "At this early stage, it appears that this was a deliberate act by the driver of the car.
"There had been an altercation in the street prior to this incident and I am appealing for any witnesses or anyone with information who has not yet come forward to contact police."
There have been no arrests and enquiries continue.
Anyone with information is asked to contact the incident room on 0208 345 3715 or call police via 101 quoting reference Cad 304/5May.
