This Sunday, Leeds United travel to League Two outfit Crawley Town in the FA Cup Third Round.
It will be the Whites' first appearance in England's oldest cup competition for a year after being gunned down 1-0 at the Emirates Stadium by Arsenal last January.
Marcelo Bielsa's side have something of an easier draw on paper this time around, but it still promises to be anything but a walk in the park.
Crawley are currently on an eight-match unbeaten run in the league, a streak only bettered by fellow Red Devils Manchester United and Brentford across the top four divisions of English football.
Premier League opponents Man United are without defeat in ten league matches, while Thomas Frank's Brentford have not lost a Championship game since October - 15 games ago.
Crawley boss John Yems has stated in no uncertain terms that his team are up for the fight, describing Leeds United as a 'free punch'.
Leeds United are no strangers to cup upsets, falling at the first hurdle on plenty of occasions before.
Famous defeats to non-league Histon and Sutton United have punctuated the Whites' recent FA Cup history.
They will be hoping in-form Crawley do not pull off a similar giant-killing at The People's Pension Stadium.
In light of the Red Devils' recent form in League Two, a run which stretches to nine games if an FA Cup victory over AFC Wimbledon is taken into account, Marcelo Bielsa may be more reserved when it comes to fielding younger players.
It is expected that those who have been squeezed out of the starting line-up such as Helder Costa, Tyler Roberts and Pablo Hernandez may feature on Sunday, but there is ample scope for some of the more impressive under-23s to feature too.
Sam Greenwood, Charlie Cresswell and Joe Gelhardt have all excelled in the first half of the Premier League 2 season under Mark Jackson, and could be in line for a call-up to the senior squad for a tantalising, classic cup clash.
Leeds' U-23 side find themselves top of the PL2 Division 2 table, with their most recent result a 7-1 hammering of Fulham at Thorp Arch.
Marcelo Bielsa undoubtedly places greater importance on the team's fortunes in the Premier League, but will still hope to avoid elimination from the FA Cup Third Round for the third consecutive campaign and a famous upset.