At least two were killed and 33 injured in Russian attacks against Ukraine overnight on Monday, regional authorities said.
An older person was killed in an attack on the city of Kupiansk in Kharkiv, Governor Oleh Syniehubov said, with two others injured.
One person was also killed in the village of Drobysheve in the Dnipropetrovsk region, where an additional three suffered injuries.
Additional strikes caused 10 injuries in the Sumy region, and three in Kherson Oblast, where Russian forces targeted 43 settlements, including the regional centre.
Overall, Ukrainian forces downed 76 out of 104 drones, including Shahed-type attack drones, launched by Russia overnight.
The strikes come despite an uptick in diplomacy focused on efforts to bring an end to Russia's all-out war against its neighbour, now well into its fourth year.
Meetings that saw US President Donald Trump speak with his Russian counterpart Vladimir Putin and Ukrainian President Volodymyr Zelenskyy have since stalled.
Trump has sought to arrange a meeting between Zelenskyy and Putin, although he acknowledged the difficulty of bringing the leaders together.
Zelenskyy on Sunday said meeting Putin would be "most effective way forward" amid efforts to end Moscow's war.
