A further three people died from COVID-19 in Perth and Kinross last week.
It is the highest weekly figure since the week beginning July 19 after a huge rise in cases.
It brings the total number of death certificates to record the coronavirus as a cause of death in the region to 272 since the crisis began last year.
The Scottish total of 58 deaths was the highest since late March, with the virus circulating more freely following the relaxation of almost all COVID restrictions by the Scottish Government last month.
However, with the vaccine programme continuing, it remains well below the peak of April last year and January this year.
The seven day COVID infection rate continues to rise in Perth and Kinross and is now at its highest level since July 10.
The current rate is 344.3 per 100,000 people, an increase from 325.2 the week before.
There were 523 positive tests in the week up to and including September 5, a rise from 494 the week before.
However, the proportion of positive tests actually dropped from 8.1 per cent to eight per cent.
The Muirton area in Perth has the highest infection rate in the region of 770.7 after 28 positive cases.
It is followed by Invergowrie, Longforgan and Abernyte (652.6) and Powmill, Cleish and Scotlandwell (600.2).
Other neighbourhoods recording a weekly infection rate over 400 are: Blair Atholl, Strathardle and Glenshee; Glenfarg, Dunning and Rhynd; Guildtown, Balbeggie and St Madoes; Letham; Blairgowrie East; Burghmuir and Oakbank; North Muirton and Old Scone; Errol and Inchture.
The lowest infection rate can be found at the Central Souch Inch neighbourhood in Perth, which has a rate of 89.1.