Fines of up to £1,500 could be handed to students who organise house parties and break social distancing rules on their return this September.
Fears have been raised by East Midlands Property Owners Group, based in Lenton, which represents around 600 landlords in the city.
Giles Inman, business development manager, said that with nightclubs still closed there is a possibility students will organise house parties instead.
They are working with the University of Nottingham and Nottingham Trent University to ensure that students are equipped with all the knowledge they need to ensure this does not happen.
He told Nottinghamshire Live: "If they are not going to pubs or clubbing what will they be doing?
"It is something we are concerned about and looking to work with our student tenants to ensure any disruption in that kind of arena is minimal for the long term residents.
"I think it is about making students aware they are living in the community.
"There is a lot of students already in situ now and it is peaceful and quiet. Maybe the reality is they are complying with guidance and not having the parties.
"There is a concern that students may spend more time in their property and there is a concern there could be more parties but it a concern by everyone, not just us."
The University of Nottingham said it will take any reports of house parties that are "out of control or have impacted on neighbours or the community very seriously."
They are also exploring the idea of extending and enhancing community protection officers in the student areas of the city.
A spokeswoman said: "Despite Nottingham's large student population, some areas such as Lenton, Dunkirk, Radford and Beeston have a number of long-term residents living there.
"As well as noise disturbance, large gatherings of people bring a greater risk for Covid-19 to spread. It’s important to maintain social distancing at all times to reduce the risk of spreading the virus."
The university said it will be extending its student disciplinary process to encompass public health protection issues as well as incidents of antisocial behaviour in the community.
The spokeswoman added: "Disciplinary measures including financial sanctions up to £1,500, suspension or exclusion are already in place for serious breaches of our code of discipline on an escalation basis."
A spokesman for Nottingham Trent University added: "Under our student code of behaviour, all students will be given clear expectations regarding the latest guidance and measures to limit the spread of coronavirus and will know they have committed to these.
"If they are found to have not followed these then there will be consequences under our disciplinary processes."
