Ibrahima Konate will make his first Anfield appearance this evening following his £36million summer move from RB Leipzig.
And 16-year-old winger Kaide Gordon also starts as Liverpool conclude their pre-season programme with a friendly against Spanish side Osasuna.
Konate will partner Joe Gomez at centre-back with Jurgen Klopp fielding an entirely different starting XI to the one that played out a 1-1 draw at home to Athletic Bilbao on Sunday afternoon.
Kostas Tsimikas is at left-back and is on standby to begin the Premier League season at Norwich City on Saturday should Andy Robertson fail to recover from the ankle injury suffered yesterday.
Neco Williams completes the defence, with Fabinho, Curtis Jones and Alex Oxlade-Chamberlain in midfield.
Roberto Firmino skippers the side and is joined in the attack by Takumi Minamino and Gordon.
Jordan Henderson and Thiago Alcantara, neither of whom have thus far featured in pre-season, are on a bench that also includes Divock Origi and Ben Davies.
Xherdan Shaqiri and Nat Phillips are again absent as a precautionary measure having also missed Sunday’s match. Both have been linked strongly with a move away from Liverpool in recent weeks.
Michael Robinson, the former Liverpool and Osasuna striker who died in April 2020, will be celebrated before the game with a period of applause.
LIVERPOOL (4-3-3) : Kelleher; N Williams, Gomez, Konate, Tsimikas; Fabinho, Jones, Oxlade-Chamberlain; Gordon, Firmino, Minamino.
Subs: Karius, H Davies, Thiago, Henderson, Origi, B Davies, R Williams, Woodburn, Beck, Cain, Clarkson, Bradley.
