Justice Secretary Dominic Raab said he has had three threats to “life and limb” over the past two years - most recently involving acid.
Mr Raab's comments come after the killing of fellow MP Sir David Amess on Friday.
He told BBC Breakfast: “There will be people who have worse abuse than me, and I particularly feel for the female MPs, and I know colleagues of mine who have come off, for example, Twitter because it’s just so vile.
“I have had three threats to life and limb over the last two years.”
He said those incidents “all resulted in an intervention”, but did not give further details.
Mr Raab said politicians deserve “maximum scrutiny” but added traditional and social media have a role to play in reducing hate.
“I think there has also been quite widespread vilification of politicians in the media,” he added.
“The constant – sometimes surreptitious, sometimes ostentatious – vilification of politicians creates the kind of climate in which these episodes take place.”
Mr Raab said the most recent threat he has received was of an acid attack.
Asked about the possibility of MPs wearing stab-proof vests, he told ITV’s Good Morning Britain: “I’m happy to look at any practical measures, but the reality is that people will threaten you with something else.
“The most recent threat I’ve had was someone threatening to throw acid over me.”
He said there was an “intervention” in relation to the threat.
Mr Raab stressed the significance of the Government’s Prevent anti-terror scheme but said he feels more at risk from “misguided or mentally unwell” people.
He told BBC Radio 4’s Today programme: “I personally think I’m more at risk from those who are either misguided or mentally unwell than from a concerted, organised terrorist attack.
“But Prevent is important.
“It is one line of defence, one mitigation against the risks we face. Prevent is under review, it has been under iterative review throughout its existence; we will of course learn all the lessons as the result of that and this terrible, appalling case.”
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