It will be a Merseyside derby with a difference this weekend.
Liverpool host their local rivals Everton in the 238th edition of one of the most storied local skirmishes in English football.
After a 68-game and near four-year unbeaten run was ended in shock circumstances by Burnley on January 21, Fortress Anfield has been left in ruins.
Subsequent defeats by Brighton and Manchester City have eroded an invincible aura that had been built since April 23 2017, when the Reds were last beaten at home in the Premier League.
Liverpool head into this one then having lost three successive league matches at Anfield for the first time since the 1960s.
The identity of the opposition - and their terrible record in front of the Kop - will not be lost on those tuning in on Saturday night, however.
Everton's awful form across the other side of Stanley Park is the stuff of Merseyside derby infamy.
Not since Kevin Campbell scored the winning goal in September 1999 have the Blues triumphed at the home of their most loathed enemy.
Everton and Liverpool have played each other 20 times there in the league since that night.
So while the prospect of seeing that proud run ended on Saturday evening is enough to make the Liverpool faithful wince even more than they have of late, there is cause for optimism.
With no fans being allowed in the ground for the game, it has allowed the kick-off time to be slated for the 5.30pm slot.
And that should be viewed as a positive omen inside an Anfield camp that has had plenty of gripes with the scheduling of their games this term.
The champions perform to their best of a Saturday night, winning 78 per cent of the games played at the time slot.
In their 27 matches that have kicked off at 5.30pm, the Reds have won a whopping 21, making the Saturday evening game their most fruitful.
Klopp has aired his grievances over the lunchtime kick-offs several times this season, particularly following the resumption of Premier League football after an international break.
“I don’t know how often I have to say it, but you picked the 12:30 kick-off, not you personally, but you did it!" Klopp told BT Sport's Des Kelly in a memorable post-match interview in November.
"Us on 12:30, between now and New Year, there’s one more Wednesday and then Saturday 12:30."
Given his side played on Tuesday night in Budapest, though, the 5.30pm slot for this weekend's derby is much more likely to be an agreeable one from Klopp's vantage point.
Even if that has only been made possible by the lack of supporters inside the ground.
Given the choice of either or, there would only be one winner for a Liverpool manager desperate to be reunited with those on the Kop.
But the Reds' record at 5:30 is at least one strong omen to take into the most important derby in years.
