Jet2 is set to make 102 pilots redundant after talks between the airline and a pilot's union failed to save jobs.
BALPA, which represents pilots, says it put forward various proposals to save jobs, but each one has been turned down.
Jet2 has a crew base at Newcastle International Airport, as well as Edinburgh, Glasgow, London-Stansted, Manchester, Birmingham and its main base in Leeds-Bradford.
Brian Strutton, BALPA General Secretary, said: "This announcement is yet another which shows the desperate state of the British aviation sector. Despite enormous efforts to work with Jet2 to find ways of saving these jobs the airline is insisting on 102 redundancies.
“This will be a particular kick in the teeth as many of those who may lose their jobs have recently joined the airline after having been dismissed from Thomas Cook which went into administration last year.
“BALPA will be supporting our pilot members in Jet2 and every other airline where they are facing the threat of losing their jobs.
“The Government has a significant role to play in supporting the vital British aviation industry. Its quarantine changes keep throwing every restart plan into chaos. If these quarantines are really needed the Government must stump up the support to help the airline industry which is doing its best to get back on track but keeps being knocked back at every juncture.”
Jet2 confirmed in June it would be making redundancies, following a hit on trade caused by the coronavirus outbreak.
At the time, Jet2 spokesperson said: "We have had to reassess and reduce our flying programme for the remainder of 2020 and for 2021. Sadly, the overall effect of these reductions has been the need to propose a number of colleague redundancies across our business.
"We cannot say how much we regret these proposed redundancies and we will be consulting with appropriate representatives of the affected colleagues in order to ensure that all options and issues are fully considered."
