James DeGale will fight Chris Eubank Jr in a domestic grudge match at The O2 in London on February 23.
The super-middleweight clash is the first of a new deal between ITV and Haymon Sports' Premier Boxing Champions, with the show set to be aired on ITV Box Office.
DeGale, 32, won the IBF super-middleweight world title for a second time in 2018 before vacating the belt.
At a press conference to announce the fight, he said: "I am really excited and looking forward to being back home to a fight of this magnitude.
"I believe Eubank doesn't have the pedigree, the size and skill to beat me.
"Eubank is a decent fighter, but every time he has stepped up he has been found out. He has called my name for a long time, so now I've finally got my chance to zip his lips."
After losing to Groves, Eubank Jr returned to the ring with victory over JJ McDonagh during September.
"DeGale is going to get the schooling of his career. A good old-fashioned hiding," Eubank Jr, 29, said.
