James Anderson has been ruled out of the second Ashes Test, with England not certain when he will be fit to return from an injured right calf.
England's record wicket-taker broke down after just four overs in the series opener at Edgbaston and did not bowl again as Australia romped to a 251-run victory.
Scans have now confirmed he has no chance of taking part in next week's game at Lord's, with assessment taking place "on an ongoing basis" regarding his comeback.
The 37-year-old was not expected to be on duty in the second Test after pulling up on the first morning in Birmingham and being restricted to two batting cameos at number 11.
The veteran had not played competitive cricket for a month leading into the match after injuring the same calf playing for Lancashire.
The England and Wales Cricket Board revealed an MRI scan had confirmed the bad news.
"The MRI confirmed that Anderson has suffered a calf injury," read a statement. "As a result of the injury, he will commence a rehabilitation programme working with the England and Lancashire medical teams.
"Anderson will miss the second Test match, which starts at Lord's on Wednesday August 14. He will be reassessed on an ongoing basis regarding his availability for the rest of Specsavers Ashes series."
