Newcastle travel to Brighton with safety now assured but this is a massive game for the Seagulls.
Former United boss Chris Hughton sees his side just three points above the drop zone after a collapse in the second half of the season.
Albion were 12th at the time they visited St James' Park, where a 1-0 win left Newcastle winless and at the bottom of the Premier League.
But Newcastle have recovered well in the second half - while Brighton need points to stave off the late challenge of Cardiff.
What time does Newcastle vs Brighton kick-off?
The action gets under way at 5.30pm.
Is Newcastle vs Brighton on TV? How can I follow it live?
The game is live on BT Sport 1 from 5pm. You can also follow all the action on ChronicleLive with our matchday live blog. We’ll be bringing you all the pre-match talk, live match commentary and any post-match reaction and analysis.
What are the injury concerns? Who is in the teams?
United will be missing Miguel Almiron and long-term absentees Sean Longstaff and Florian Lejeune are also out.
Fabian Schar and Isaac Hayden have been passed fit despite concerns, although Jamaal Lascelles is also absent.
Newcastle United dealt big injury blow as in-form skipper is ruled out of Brighton clash
Newcastle likely XI: Dubravka; Javi Manquillo, Lascelles, Schar, Dummett, Ritchie; Perez, Ki, Hayden, Atsu; Rondon.
Brighton likely XI: Ryan; Bruno, Duffy, Dunk, Bong; March, Stephens, Bissouma, Izquierdo; Gross; Murray.
Who is the ref?
It's Mike Dean for the match on Saturday. He sparked fury from some Newcastle fans for his officiating in the Wolves home game earlier this season, when he sent off DeAndre Yedlin but missed an elbow from Wily Boly against Wolves.
What are the bookies saying?
Newcastle 13/5
Brighton 11/8
Draw 9/4
