Ireland will host reigning Guinness Six Nations champions Wales in the opening match of the 2022 championship.
Andy Farrell's side will kick off the tournament at the Aviva Stadium on Saturday, February 5.
The Celtic rivals met in Cardiff in the opening round this year, with Peter O'Mahony's first half red card proving costly and Ireland losing 21-16.
Scotland will host England on the same day while France will face Italy at the Stade de France on Sunday 6th February.
There will be a return of Friday night rugby in Round 4 with Wales v France set to take place on 11th March at the Principality Stadium in Cardiff.
Super Saturday 2022 will take place on 19th March starting with Wales v Italy followed by Ireland v Scotland and France v England.
After hosing the Welsh, Ireland will travel to Paris to face France seven days later before taking on Italy at home on Sunday, February 27.
They will clash with England at Twickenham on Saturday, March 12 before the final game against the Scots seven days later.
Commenting on the announcement, Six Nations CEO, Ben Morel said: "The 2021 Championship was one of the most competitive in history with 8 of the 15 matches won by 7 points or less.
"The drama of Super Saturday with France’s last minute win against Wales, meant that the winner of the Championship was only revealed after the final match was played.
"It was an amazing effort from many people to make the Championship happen, not least the players and staff from the unions, the broadcasters, media and our partners.
"That effort paid off in the shape of record TV audiences and the most engaged Championship we’ve ever seen, it was truly a special achievement. This Guinness Six Nations entertained many of our long-standing fans and I believe we won plenty of new ones as well.
"We look forward to next year’s Championship with hopefully a return to normality when we can welcome fans back in stadia and bring that unrivalled Guinness Six Nations atmosphere into sitting rooms, pubs and rugby clubs all over the world."
* Kick off times will be announced in due course.
