Prime Minister Rishi Sunak has apologised to the victims of the infected blood scandal and their families.
It comes after an an inquiry into the biggest treatment disaster in the NHS concluded the scandal "could largely have been avoided" and there was a "pervasive" cover-up to hide the truth.
Mr Sunak told the Commons: “This is a day of shame for the British state.
“Today’s report shows a decades long moral failure at the heart of our national life – from the National Health Service to the civil service, to ministers in successive governments, at every level the people and institutions in which we place our trust failed in the most harrowing and devastating way.
“They failed the victims and their families and they failed this country.”
He promised to pay “comprehensive compensation” to those affected and infected during the scandal.
“Whatever it costs to deliver this scheme, we will pay it,” he added, saying details would be set out on Tuesday.
Deliberate attempts were made to conceal the disaster, including evidence of Whitehall officials destroying documents, the Infected Blood Inquiry found.
Patients were knowingly exposed to unacceptable risks of infection, the probe found.
The 2,527-page report published on Monday documents a "catalogue of failures" which had "catastrophic" consequences, not only among people infected with contaminated blood and blood products, but also their loved ones.
More than 30,000 people were infected with deadly viruses while they were receiving NHS care between the 1970s and 1990s, in a disaster described by inquiry chairman Sir Brian Langstaff as a "calamity".
Sir Brian said "the scale of what happened is horrifying", with more than 3,000 people dead as a result and survivors battling for decades to uncover the truth.
Kate Burt, chief executive of the Haemophilia Society, said: "This report vindicates the long-held beliefs of survivors that the Government hid the truth to protect itself and to save money. The tragic truth is that many of the infections could and should have been prevented."
