Donald Trump recorded a brief video message on Friday before departing for Walter Reed hospital, where he will undergo treatment for the coronavirus.
"I want to thank everybody for the tremendous support. I’m going to Walter Reed hospital. I think I’m doing very well, but we’re going to make sure things work out," he said in a short video filmed in the Oval Office.
"The First Lady is doing very well. So thank you very much, I appreciate it. I will never forget it," he added.
Mr Trump tested positive for the virus late on Thursday evening and airlifted to hospital some 17 hours later after suffering chills and a fever throughout the day.
White House press secretary Kayleigh McEnany said Mr Trump will work in a special suite at the hospital for the next few days as a precautionary measure.
White House doctor Sean P. Conley said the president is being treated with an experimental drug cocktail and is "fatigued but in good spirits."