Hundreds of anti-lockdown protesters marched through the Arndale shopping centre.
It's understood that the rally was held in protest against current Covid-19 restrictions.
Pictures and videos from the protest show hundreds of people walking through the Arndale carrying anti-lockdown banners earlier today.
Few appear to be wearing masks. GMP said nobody was arrested in the protest.
The protest was held two days ahead of the next national easing of lockdown restrictions.
The demonstrators continued their protest through the city centre, marching through Chapel Street in Salford before ending up in Media City.
From Monday people from different households will be able to mix indoors for the first time in months, although some restrictions will still apply.
Pubs and restaurants will be able to serve customers indoors in groups of up to six people, although they will be limited to table service.
People in England will be able to meet outdoors in groups of up to 30, and indoors - including private homes - in groups of six, or two households.
Close contact between friends and family will also be allowed to resume, meaning people can finally hug again.
Other recreational venues such as cinemas, museums, theatres and concert halls will be allowed to reopen, although there will be capacity limits on large events.
