Barcelona have problems in attack for Sunday night's La Liga clash at home to Real Betis as Lionel Messi, Luis Suarez and Ousmane Dembele are all out.
Messi is still recovering from a calf injury and has been left out after only returning to full training on Wednesday, while Suarez is sidelined with a similar problem sustained in last Friday's 1-0 loss away to Athletic Club at San Mames and Dembele was ruled out for five weeks on Monday with a hamstring issue.
With Malcom sold to Zenit Saint Petersburg earlier in the summer and Philippe Coutinho now on loan at Bayern Munich, options are limited for coach Ernesto Valverde in the second round of the competition.
Summer signing Antoine Griezmann is a certain starter at Camp Nou and he could be joined in attack by Rafinha, who was Barca's best player at San Mames.
Young striker Carles Perez could also feature from the outset after coming off the bench in Bilbao, while Valverde has called up 16-year-old forward Ansu Fati, who plays for the club's Juvenil A side.
Midfielders Arthur and Arturo Vidal are back in the squad after they were left out for the trip to the Basque Country, while Carles Alena drops out after a disappointing display at San Mames.
Sergio Busquets is expected to return after he was benched in Bilbao and Valverde could decide to play a 4-4-2 formation as several of his attackers are out.
Junior Firpo will start as a substitute but may play some part against his former club, having scored in this fixture last season in a surprise 4-3 win for Betis.
Back-up goalkeeper Neto is sidelined.
Predicted Barcelona XI: Ter Stegen; Semedo, Pique, Lenglet, Alba; Busquets, De Jong, Rakitic; Rafinha, Carles Perez, Griezmann
