Bristol's shopping areas have seen some high-profile stores close in recent months.
Among those are the Park Street branch of denim brand Levi's and the Patisserie Valerie cafe in Queens Road.
The Government is considering how it can help high streets across the country emerge from the challenging climate.
Last month local authorities were urged to "get to grips with the fact that their town centres need to change", in a Housing, Communities and Local Government Committee's (HCLG) report.
It called for business rates to be "made fair", arguing "they are currently stacking the odds against businesses with a high street presence and this must end".
Aldi is bringing back its inflatable hot tub at a ridiculously cheap price
We have looked at how much traders would have to pay in rates and rent if they were to open businesses in some of Bristol's empty units.
The following list shows these costs and how they vary across the city.
28 St Augustine’s Parade, city centre
Most recently occupied by: The Co-op supermarket
Rent for year: £57,500
Business rate for year: £32,291.50
Bristol Asda and Sainsbury's could be sold off amid proposal to 'sell up to 150 supermarkets'
Total yearly cost: £89,791.50
81 Park Street, city centre
Most recently occupied by: Levi’s clothing store
Rent for year: £67,500
Business rate for year: £29,087
Total yearly cost: £96,587
49 Queens Road, Clifton
Most recently occupied by: Jones Bootmaker
Rent for year: £49,500
Business rate for year: £17,760
Squatters evicted from former supermarket in Bristol city centre
Total yearly cost: £67,260
57 Queens Road, Clifton

Most recently occupied by: Patisserie Valerie cafe
Rent for year: £47,500
Business rate for year: £15,480
Total yearly cost: £62,980
142 Whiteladies Road, Clifton
Most recently occupied by: Betfred
Rent for year: £21,744
New shop opening in Weston-super-Mare aims to help people struggling to cope
Business rate for year: £15,480
Total yearly cost: £37,224
107 East Street, Bedminster

Most recently occupied by: Bristol Bridal Boutique
Rent for year: £9,950
Business rate for year: £4,608
Total yearly cost: £14,558
31 Regent Street, Clifton
Most recently occupied by: G&T Hairdressing
Rent for year: £17,900
There will be a pop-up Co-Op supermarket at Glastonbury Festival for 2019
Business rate for year: £8,160
Total yearly cost: £26,060
12 Baldwin Street, city centre
Most recently occupied by: Santander
Rent for year: £41,000
Business rate for year: £14,280
Total yearly cost: £55,280
Unit 1, Hengrove Leisure Park
Most recently occupied by: Oriental Buffet
Rent for year: £25,000
Business rate for year: £16,080
Shopping centre to undergo major revamp and 420 flats to be built
Total yearly cost: £41,080
42-44 High Street, Westbury-on-Trym
Most recently occupied by: McColl’s
Rent for year: £22,802
Business rate for year: £12,840
Total yearly cost: £35,642
Bristol City Council was approached for comment.