Manchester United and Arsenal both missed the chance to move into the top four on Wednesday night.
A spirited United display wasn't enough to prevent Man City moving closer to securing back-to-back with a 2-0 win at Old Trafford.
Arsenal completed a miserable few days with a 3-1 loss to Wolves after their previous 3-2 defeat to Crystal Palace on Sunday.
Spurs are now looking very strong for a place in the top four after their 1-0 win over Brighton & Hove Albion on Tuesday night.
Gary Neville and Jamie Carragher disagree over Jesse Lingard tackle in Manchester United vs Man City
The latest odds reflect that with Tottenham the 1/50 favourite to cement a Champions League spot.
Man United are now expected to miss out on the top four according to the bookmakers with Chelsea also expected to finish the season strongly.
United take on Chelsea in a must-win Premier League game on Sunday if they want to be competing in the Champions League next season.
Premier League top four finish odds (SkyBet):
Tottenham - 1/50
Chelsea - 4/5
Arsenal - 11/10
Manchester United - 6/1
Roy Keane explains the key differences between Man City and Manchester United
