The deadly Hendra virus has been detected on a Queensland horse for the first time in five years.
A Department of Agriculture and Fisheries spokesperson said the virus was found in a horse on a Mackay property on Friday.
Biosecurity Chief Veterinary officer Allison Crook said the horse's condition deteriorated rapidly, with the animal having to be euthanased.
It is understood the horse had not been vaccinated against the virus.
"Tracing and risk assessments have been undertaken on other animals on the property," Dr Crook said.
"We are also working with Queensland Health's Public Health experts to determine if any humans had contact with the infected horse and stand ready to provide any assistance, counselling, information, testing or treatment that may be required."
Dr Crook said the Hendra virus infection could occur throughout the year and for owners to contact their veterinarian immediately if their horse became sick.
Biosecurity Queensland's Fiona Thompson said there were typically two types of syndromes of the virus.
Ms Thompson advised owners to get their horses vaccinated and to limit their contact with flying foxes.
She said this could involve covering water containers and feeding them undercover.
