A gunman opened fire outside a busy row of shops after witnesses heard 'loud bangs' in the area.
Emergency services were called to Hillside Road, near Longview shops, shortly before 10pm on Monday night.
Reports were made about a number of 'loud bangs' as police rushed to the scene to investigate the shooting.
READ MORE: Mum 'severely injured' after being knocked down in car park
Evidence of shots being fired were found at the scene as detectives work to find out whether anyone was injured in the attack.
A number of cordons and road closures were put in place around the scene of the shooting.
Members of the public reported seeing a police helicopter over the nearby houses.
In a statement, a spokesperson for Merseyside Police said: "We are appealing for information after shots were fired in Huyton tonight, Monday 16 August.
"At around 9.45pm, armed officers were called to Hillside Road to reports of shots being fired near to Longview shops.
"Evidence has been found to confirm shots were fired, and enquiries are ongoing to confirm if anyone was injured.
"House-to-house, CCTV and witness enquiries continue at the scene and officers will remain in the area to speak to the community and gather information."
Officers are now also asking people to report any vehicles they seen speeding from the area after the shooting.
Chief Inspector Geoff Stewart said: “These are the early stages of an investigation, during which it is establish exactly what happened tonight, and preserve any evidence. If you were in the area, passing by or live locally, you could be able to help.
"Your CCTV, dashcam, doorbell footage may present us with opportunities to find those responsible and quickly take them and their weapon off the streets.
“If you heard or saw anyone suspicious in the area tonight, or any vehicles driving off at speed around 9.45pm, check any devices which could capture that detail.
“When communities stand strong and pass on information, to us or via other channels, we can make these safer places to live and work, and ensure those who would endanger the public are put behind bars.
"Gun crime in Merseyside has fallen dramatically in the past few years, due in no small part to those people prepared to speak to us, directly or anonymously.
"However you choose to tell us, please come forward.”
Contact police via @MerPolCC on Twitter or Merseyside Police Contact Centre on Facebook, with reference 989.
You can also pass information anonymously via Crimestoppers on 0800 555 111, or contact them via their online form at: https://crimestoppers-uk.org/give-information/give-information.
Always call 999 if a crime is in progress.
