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The Independent UK
The Independent UK
National
Storm Newton

Groundbreaking treatment gives hope to people with untreatable blindness

  • A groundbreaking, low-cost gel injection has successfully restored sight in patients suffering from hypotony, a rare and previously untreatable form of blindness caused by abnormally low eye pressure.
  • Pioneered by London's Moorfields Eye Hospital, the treatment involves injecting hydroxypropyl methylcellulose (HPMC) directly into the eye, which acts like a filler to normalise pressure and restore the eye's shape.
  • In a study published in the British Journal of Ophthalmology, seven out of eight patients experienced restored vision after 12 months of treatment, with no serious side effects reported.
  • The HPMC gel offers a significant improvement over the previous standard treatment of silicone oil, which can cause toxicity and impair vision due to its light-bending properties.
  • Consultant ophthalmologist Harry Petrushkin, who leads the world's only hypotony clinic at Moorfields, is now seeking funding for a larger clinical trial and working to develop longer-lasting gel products.

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