Grimsby Town's reward for toppling Manchester United in the Carabao Cup is a third-round trip to crisis club Sheffield Wednesday.
The League Two Mariners pulled off one of the biggest shocks in the competition's history by beating the Premier League giants following a mammoth penalty shootout and will now travel to Hillsborough with a realistic shot of making the fourth round.
Liverpool will host Southampton and there is also a home tie for defending champions Newcastle as they welcome League One Bradford.
Arsenal, Chelsea, Tottenham and Manchester City will all also face third-tier opposition.
The Gunners visit Port Vale, Enzo Maresca's side head to Lincoln, Spurs host Doncaster, while City begin their quest to win the League Cup for the first time since 2021 with a trip along the M62 to face Huddersfield.
There are all-Premier League clashes as Brentford host Aston Villa, who met at the weekend in the league, and Wolves entertain Everton.
Nottingham Forest visit Championship side Swansea while Crystal Palace host Millwall in a repeat of last season's fiercely-contested FA Cup tie, which saw Jean-Philippe Mateta suffer a serious head injury.
Burnley host Cardiff, Brighton travel to League One Barnsley, Fulham host Cambridge, Wrexham welcome Reading and Wigan play Wycombe.
Ties will be played in the weeks commencing 15 and 22 September.
Carabao Cup third round ties
matches to be played on w/c 15 September:
Sheffield Wednesday vs Grimsby Town
Wolves vs Everton
Crystal Palace vs Millwall
Burnley vs Cardiff
Wrexham vs Reading
Wigan Athletic vs Wycombe
Barnsley vs Brighton
Fulham vs Cambridge
Matches to be played on w/c 22 September:
Port Vale vs Arsenal
Swansea City vs Nottingham Forest
Lincoln City vs Chelsea
Tottenham Hotspur vs Doncaster
Brentford vs Aston Villa
Huddersfield Town vs Manchester City
Liverpool vs Southampton
Newcastle vs Bradford City
PA
