A widow from Gateshead has claimed that her late husband's death in 2010 may have been caused by vaping.
Terry Miller was only 57 when he died after developing lipoid pneumonia - when fat particles enter the lungs.
After his death, doctors told Terry's wife Glynis that oil from vaping fluid was found in the lungs of her husband.
Glynis is now calling for a new inquest after the first recorded an open verdict, The Mirror reports.
She believes her husband's vaping habit could have hastened his death, claiming he was better off smoking.
Glynis also believed Public Heath England did not have enough evidence at the time on the risks of e-cigarettes.
The case was highlighted after a report from the Medicines and Healthcare Products Regulatory Agency said vaping affected the health of 200 British e-cigarette users.
In America, there are fears that 13 people have died due to vaping and more than 800 have fallen ill.
Despite fears, experts claim vaping should be considered far less harmful than smoking.
However, Glynis said e-cigs "lull people into a false sense of security".
She added: "The doctor took me into a room as Terry's condition deteriorated and told me he was as certain as he could be that it was caused by the e-cigarette.
"People ask, do you think vaping caused his death? I can't say definitively that it did, only that it very much contributed.
"If he hadn't used the e-cigarette and carried on smoking, I don't think he'd have died at the age of 57."
However, experts claim vaping has helped thousands of smokers to quit tobacco.
NHS Professor John Newton said: "It isn't risk-free but it is far less harmful than smoking.
"It would be tragic if smokers who could quit with the help of an e-cigarette did not do so because of false fears about their safety."
Experts are now calling for a national system to record every problem associated with e-cigarettes amid increasing concern over their safety, according to The Sunday Times .
They have already been banned in Brazil, India, Thailand and Singapore.
