Gary Neville insisted Manchester United can't afford to rest Bruno Fernandes or Harry Maguire as they are "irreplaceable".
Both players started Wednesday night's 2-0 victory over Everton in the Carabao Cup quarter-finals, while David de Gea, Victor Lindelof and Marcus Rashford were all rested.
Maguire has made 20 appearances for United already this term and Fernandes one extra, making them two of Ole Gunnar Solskjaer's ever-presents.
Fernandes has contributed to 29 goals in 27 Premier League matches since his arrival, while Maguire is now club captain and a leader on and off the field.
Neville believes that Maguire and Fernandes are two of United's "irreplaceable" players in the current squad and can't afford to be rested.
Speaking on his Sky Sports Podcast, Neville said: "They are the two players who I think are irreplaceable. Fernandes is irreplaceable, they are a way off without him. He’s a vital piece of the jigsaw.
"Maguire, I think, you’d know if he was missing. My gut feeling is that they would miss him enormously.
"I know some people say he’s not the best defender in the league, that he’s not done brilliantly since he came for £80m, but he’s a big presence in the heart of the defence. He’s good on the ball, he’s composed and he’s good in the air.
"He doesn’t make a lot of mistakes, sometimes he gets caught but he’s a good centre-back, a really good centre-back and a big presence in that team.
"Him and Fernandes, I’m not sure they can [rest them] at this moment in time because Ole hasn’t got the luxury to lose a game, unfortunately."
