Donald Tusk launched a scathing attack on Donald Trump and Boris Johnson as world leaders arrived in France for the G7 summit.
The European Council president warned Mr Johnson could go down in history as "Mr No Deal" before the prime minister had even touched down.
But speaking on the plane to Biarritz, Mr Johnson retaliated by suggesting a failure to reach a Brexit agreement would also reflect badly on Mr Tusk.
The prime minister is preparing for his first international summit and meeting with US president Donald Trump since he entered Downing Street.
Ahead of the summit, which continues until Monday, Mr Johnson warned his Brexit critics they were “gravely mistaken” about the UK losing its place on the world stage.
"To those people I say: you are gravely mistaken."

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The prime minister meets the US president at the G7 meeting of world leaders in Biarritz this weekend
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Innovators offered the chance to bid for £300m of government and industry cashMr Macron, the French president, said Mr Bolsonaro had lied in playing down concerns about climate change at a G20 summit in Japan in June, and threatened to veto a trade pact between the European Union and the Mercosur bloc of South American countries.
Greenpeace called the deforestation an emergency that highlighted the G7 leaders' need to act on ending fossil fuels and protecting forests.
"France and other developed countries are responsible for the dire Amazon situation through their economies and contribution to imported deforestation, fuelled by ill-designed policies in sectors like agriculture, timber and bio-energies."
"Our Country has lost, stupidly, Trillions of Dollars with China over many years," Mr Trump tweeted. "We don't need China and, frankly, would be better off without them."
Xi Jinping, China's president, is not among the Asian leaders invited to the Biarritz summit.

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‘Macron is hoping to get out of Biarritz with no blood on the floor’South Korea canceled a deal to share military intelligence, mainly on North Korea, after a trade dispute between the two countries.
Relations between two countries, both allies of the US, are at their lowest point since they established diplomatic ties in 1965.
Protesters planned to cross into Spain from the French border village town of Hendaye.
Mr Macron, the French president and host, put the Amazon fires at the top of the agenda for the weekend meeting.
"The EU was always open to co-operation when David Cameron wanted to avoid Brexit, when Theresa May wanted to avoid a no-deal Brexit and we will also be ready now to hold serious talks with Prime Minister Johnson.
Cedric O, a French official in charge of digital economy, told reporters that the other six nations in the G7 have already backed the pledge, as have Google and Facebook.
The US did not endorse a similar pledge after the mosque attack in Christchurch, New Zealand, earlier this year.
Germany is backing the French president Emmanuel Macron's call to discuss the fires at the weekend's French-hosted G7 summit.
She said leaders are "shaken" by the fires and that they will discuss "how we can support and help there, and send a clear call that everything must be done so that the rainforest stops burning."
Amid a series of policy and trade disagreements, which she didn't address explicitly, Ms Merkel said that "talking to each other is always better than about each other — and the G7 is an excellent opportunity for that."

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‘We have to work collectively’On Friday, Mr Macron, the French president, threatened to block the recently agreed trade deal with Mercosur, which also includes Argentina, Paraguay and Uruguay. Ireland joined in the threat.
Ms Merkel, the German chancellor, has made clear she shares Mr Macron's concern about the fires.
It added: "The non-conclusion [of the deal] is therefore from our point of view not the appropriate response to what is currently happening in Brazil."