Arsenal are looking to bounce back from their disappointing FA Cup exit at the hands of Southampton when they tackle Ralph Hasenhuttl's side in a rematch this evening.
The Gunners' defence of the crown they lifted at Wembley Stadium last year ended in a whimper, emphasising the importance of the league campaign and continental exploits in the Europa League.
In the Premier League, Arsenal are enjoying a five-match unbeaten streak stretching back to the pre-Christmas victory over Chelsea but the clash against Southampton is the start of a testing run of fixtures for Mikel Arteta's side.
While there has been considerable improvements in the past month following a disappointing run previously, there is a danger that the pressure will reignite over the course of the coming weeks.
Arteta does have some issues heading into the clash against Southampton though, with the biggest concern surrounding captain Pierre-Emerick Aubameyang who missed the FA Cup clash due to personal reasons and is a major doubt for the midweek tie.
Pablo Mari will miss the clash due to a calf injury but could return for next week's clash against Manchester United, while Dani Ceballos could return after missing the FA Cup clash through injury.
Full Arsenal squad available to face Southampton:
Goalkeepers: Bernd Leno, Runar Runarsson, Mat Ryan.
Defenders: Hector Bellerin, Gabriel Magalhaes, David Luiz, Rob Holding, Cedric Soares, Calum Chambers, Kieran Tierney.
Midfielders: Granit Xhaka, Mohamed Elneny, Ainsley Maitland-Niles, Joe Willock, Emile Smith Rowe, Bukayo Saka, Willian, Nicolas Pepe, Reiss Nelson, Dani Ceballos (if fit).
Forwards: Alexandre Lacazette, Eddie Nketiah, Gabriel Martinelli, Folarin Balogun.
