The Foreign Office had changed its travel advice to advise against "all but essential travel" to mainland Spain.
The major announcement comes following a spike in coronavirus cases in some Spanish regions- such as Aragon, Navarra and Catalonia.
The updated advice states that the decision was taken "based on the current assessment of Covid-19 risks".
The Canary Islands and the Balearic Islands are exempt from the travel advice, although travellers returning from those islands will still need to self isolate for two weeks upon returning after it was removed from the travel corridors list.
Advice on the Foreign Office website states: "From 26 July, the FCO advises against all non-essential travel to mainland Spain based on the current assessment of Covid-19 risks.
"Only the Canary Islands (Tenerife, Fuerteventura, Gran Caneria, Lanzarote, La Palma, La Gomera, El Hierro, and La Graciosa) and Balearic Islands (Mallorca, Menorca, Ibiza and Formentera) are exempt from the FCO advice against all non essential international travel.
"This advice is based on evidence of increases in cases of Covid-19 in several regions, but particularly in Aragon, Navarra, and Catalonia (which include the cities of Zaragoza, Pamplona and Barcelona).
"The FCO is not advising those already travelling in Spain to leave at this time. Travellers should follow the advice of the local authorities on how best to protect themselves and others, including any measures that they bring in to control the virus.
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"If you are returning from Spain (including from the Balearics and Canaries) on or after 26 July you will be required to quarantine on your return to the UK, but the FCO is not advising you to cut short your visit. You should contact your tour operator or airline if you have any questions about your return journey.
"PHE are continuing to monitor the situation in the Balearic and Canary Islands closely. Travellers there should continue to check this advice regularly.
Britons arriving in Spain will not have to self-isolate when they arrive in Spain but they will have to provide the Spanish Ministry of Health with contact information and any history of exposure to coronavirus 48 hours prior to travel.
