Sadio Mane will miss Liverpool's trip to face Aston Villa on Sunday in the Premier League after testing positive for Covid-19.
The Reds star attacker was the second player this week among Jurgen Klopp's squad to contract coronavirus, after it was confirmed Thiago Alcantara had also recorded a positive test.
Mane's positive test will come as a blow to the manager as he would have been in line to start at Villa Park in the 7pm kick-off this weekend, with the Premier League champions looking to continue their so far perfect start in defence of the title.
However, he will be unavailable due to having now started a 10-day period of self-isolation - in line with necessary Government protocols.
It will also mean he will be forced to withdraw from international duty with Senegal next week too, with his country playing two friendlies against Morocco and Mauritania.
Liverpool will be hoping that Mane recovers well and comes out of self-isolation with a strong health and fitness in order to be available to play Everton in the Merseyside derby at Goodison Park on Saturday, October 17.
A statement from the club said Mane "has displayed minor symptoms of the virus but feels in good health overall".
Latest Premier League coronavirus testing results
The Premier League confirmed last Monday that that there had been 10 new positive Covid-19 tests between September 21 and September 27.
This was from 1,595 players and club staff tested for the virus.
Previous test results
Round 1: 31 Aug-6 Sep - 1,605 tested, with three testing positive.
Round 2: 7-13 Sep - 2,131 tested, with four testing positive.
Round 3: 14-20 Sep - 1,574 tested, with three testing positive.
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