First Minister Mark Drakeford said Wales will not lift all coronavirus restrictions on June 21 even if England does and is following its "own timetable".
England's roadmap for easing lockdown has indicated that all "legal limits on social contact" will end on June 21, less than three weeks away.
The First Minister has now confirmed that Wales will not follow this easement of restrictions, even if England does, following a meeting with other UK leaders on Thursday.
Speaking to Good Morning Britain on Friday, ahead of announcing changes to lockdown in Wales, Mr Drakeford said: "If England were to lift all restrictions on June 21, that would not be the case in Wales."
Mr Drakeford did however add that he expects life in Wales to be "significantly back to as it was before" coronavirus, but stressed some things are too risky.
He said: "Life in Wales will be very significantly back to as it was before but there still will be some things that we think are too risky but we will not be allowing those until we are more certain that we have got everybody vaccinated, at least with a first dose and as many people as possible with a second dose.
"So we have more protection from any new dangers from this virus that has had many many surprises up its sleeve that we are as confident as we can be that we have built those protections as high as we can."
He spoke more about his plans for further lockdown easing this summer, speeding up vaccinations and the Indian variant in an interview with WalesOnline this morning - see that full interview here.
The UK Government hopes to remove "all legal limits on social contact" from June 21, but some things like mask wearing and social distancing may remain in place.
But Mr Drakeford said Wales will be sticking to its "own timetable." He told BBC Radio Wales: "We have our own timetable.
"We have a three-week cycle for decision making. It's stood us in very good stead. It's helped us to get to the position we're in Wales today - the lowest coronavirus figures anywhere in the UK and the best vaccination figures anywhere in the world.
"We will stick to that careful, cautious, regular rhythm of decision making we have taking the decisions that are right for Wales. I don't intend to move away from that."
Wales is expected to look at the easing of restrictions on indoor contact on June 21 at its next review.
Changes on the amount of people that can attend outdoor events in Wales were announced on Friday and will start on Monday. You can see all the changes here.
In relation to the changes announced on Friday, Mr Drakeford said that outdoor sporting venues and concert venues will have to carry out a risk assessment on their own premises that will set their own capacity for fans after it was announced a maximum of 4,000 non-seated and a maximum of 10,000 people seated could attend sporting events and concerts.
He told BBC Radio Wales: "Just to be clear, that is the maximum number, every venue will have to carry out a risk assessment, every venue will have to set the maximum number that it can accommodate because sporting events vary enormously in their size and scale. So just across the border, as we have seen in pilot events in Wembley, the fact that there is a maximum number it does not mean that every venue will reach the maximum."
The UK Government has been warned to delay the lifting of lockdown on June 21 due to the Indian variant, now called the Delta variant, of the virus.
Professor Ravi Gupta, a member of the New and Emerging Respiratory Virus Threats Advisory Group told Sky News that a further easing of measures on June 21 was "a bit early" and said he thinks it should be delayed by a month.
He said: "I think we need at least a few weeks - probably a month until schools have closed, when the risk of transmission within schools falls during summer holidays.
"It then gives us another four weeks' worth of data to collect about how the (Indian variant of the) virus is growing in the population, what sort of rate it is growing at, how it is doing relative to the previous strain B117.
"And also how effective our vaccines are against this new virus.
"All of that information is coming in weekly and it will enable us to build up a better picture whilst staying safe and maintaining the gains we made through that really painful three of four months we had."
