Fifa 19 will include the Champions League, as part of a major break with tradition.
The move was announced during E3, where companies including Fifa developer EA revealed their plans for the future.
The tournament has been Fifa's most glaring omission among what is otherwise an incredibly detailed and highly-licensed game. It includes most of the world's leagues and has even introduced a special mode for the World Cup, which this year came as a free update.
Until now, the Champions League has been the preserve of Konami's Pro Evolution Soccer series. But it has now split from that game.
Fifa developer Electronic Arts (EA) also used their showcase event on Saturday to announce a comeback for popular military strategy game Command & Conquer, with a new mobile game called Rivals previewed at the event.
On the introduction of the Champions League to Fifa 19, EA Sports executive producer Aaron McHardy said: "The UEFA Champions League has been one of the most requested features from players for over a decade, and we're so excited for one of the world's biggest competitions to join 'The World's Game' in Fifa 19.
"We are elevating the experience this year in so many ways, from integrating UEFA Champions League content across the game, to adding a variety of new features that bring more control to gameplay."
The trade show will also feature appearances from other long-running and popular series, with new details on the upcoming Assassin's Creed Odyssey and Shadow of the Tomb Raider expected during the show.
Fellow gaming industry heavyweights Sony and Nintendo will make their own gaming announcements before the convention's doors open, with reports suggesting Nintendo may confirm current gaming craze Fortnite is to be launched on the Japanese firm's Switch console.
Additional reporting by agencies
