Liverpool host Arsenal in Saturday's headline fixture as the Reds aim to maintain their title lead a preserve an unbeaten Premier League run dating back to May.
The Gunners have won just once in four matches in all competitions and Unai Emery will be keen to put that record right as the race for a Champions League spot heats up heading into the New Year.
Elsewhere, Tottenham host Wolves having scored 11 goals in their last two games over the festive spell, and Mauricio Pochettino's men will be keen to slice the title lead ahead of Liverpool's evening kick-off.
Relegation-threatened Fulham welcome fellow strugglers Huddersfield to Craven Cottage for a six-pointer, while Chelsea travel across London to Crystal Palace in Sunday's early kick-off.
In-form West Ham visit Burnley and Man CIty will be aiming to avoid a third straight defeat when they travel to the south coast to play Southampton, where the champions celebrated reaching 100 points on the final day of last season.
Ole Gunnar Solskjaer's Manchester United host Bournemouth to round off another bumper slice of festive football.
Here’s how the EPL table looks ahead of gameweek 20…
| Pos | Team | P | W | D | L | GD | Pts |
| 1 | Liverpool | 19 | 16 | 3 | 0 | 36 | 51 |
| 2 | Tottenham | 19 | 15 | 0 | 4 | 24 | 45 |
| 3 | Man City | 19 | 14 | 2 | 3 | 36 | 44 |
| 4 | Chelsea | 19 | 12 | 4 | 3 | 21 | 40 |
| 5 | Arsenal | 19 | 11 | 5 | 3 | 16 | 38 |
| 6 | Man Utd | 19 | 9 | 5 | 5 | 6 | 32 |
| 7 | Leicester | 19 | 8 | 4 | 7 | 2 | 28 |
| 8 | Everton | 19 | 7 | 6 | 6 | 2 | 27 |
| 9 | West Ham | 19 | 8 | 3 | 8 | -1 | 27 |
| 10 | Watford | 19 | 8 | 3 | 8 | -1 | 27 |
| 11 | Wolves | 19 | 7 | 5 | 7 | -2 | 26 |
| 12 | Bournemouth | 19 | 8 | 2 | 9 | -6 | 26 |
| 13 | Brighton | 19 | 6 | 4 | 9 | -6 | 22 |
| 14 | Crystal Palace | 19 | 5 | 4 | 10 | -8 | 19 |
| 15 | Newcastle | 19 | 4 | 5 | 10 | -12 | 17 |
| 16 | Southampton | 19 | 3 | 6 | 10 | -15 | 15 |
| 17 | Cardiff City | 19 | 4 | 3 | 12 | -20 | 15 |
| 18 | Burnley | 19 | 3 | 3 | 13 | -24 | 12 |
| 19 | Fulham | 19 | 2 | 5 | 12 | -26 | 11 |
| 20 | Huddersfield | 19 | 2 | 4 | 13 | -22 | 10 |
EPL fixtures | gameweek 20
| Saturday, December 29 | Kickoff (GMT) | Coverage | TV |
| Brighton vs Everton | 3pm | ||
| Fulham vs Huddersfield | 3pm | Preview | |
| Leicester vs Cardiff | 3pm | ||
| Tottenham vs Wolves | 3pm | Preview | |
| Watford vs Newcastle | 3pm | ||
| Liverpool vs Arsenal | 5.30pm | Preview | BT Sport |
| Sunday, December 30 | |||
| Crystal Palace vs Chelsea | 12pm | Preview | Sky Sports |
| Burnley vs West Ham | 2.15pm | Preview | |
| Southampton vs Man City | 2.15pm | Preview | Sky Sports |
| Man Utd vs Bournemouth | 4.30pm | Preview | Sky Sports |
EPL results | gameweek 19
| Wednesday, December 26 | Kickoff (GMT) | Coverage | TV |
| Fulham 1-1 Wolves | 12.30 | Report | Sky Sports |
| Burnley 1-5 Everton | 3pm |
| |
| Crystal Palace 0-0 Cardiff | 3pm | Report | |
| Leicester City 2-1 Man City | 3pm | Report | |
| Liverpool 4-0 Newcastle | 3pm | Report | |
| Man Utd 3-1 Huddersfield | 3pm | Report | |
| Tottenham 5-0 Bournemouth | 3pm | Report | |
| Brighton 1-1 Arsenal | 5.15pm | Report | Sky Sports |
| Watford 1-2 Chelsea | 7.30pm | Report | Sky Sports |
| Thursday, December 27 | |||
| Southampton 1-2 West Ham | 7.45pm | Report | Sky Sports |
