Wales head coach Ioan Cunningham has made five changes to the side which has started their Six Nations campaign with back-to-back wins.
His side, unchanged up until now after they came from behind to win against both Ireland and Scotland, now face reigning champions England at Gloucester's Kingsholm on Saturday (4.45pm kick-off, live on BBC Two).
Donna Rose starts at loosehead prop after an impressive display off the bench against Ireland where she scored two tries. Sisilia Tuipulotu has been handed her first international start at lock. In the back-row, Sioned Harries - player of the match and try-scorer against Scotland - comes in at No. 8 after two strong cameos off the bench, meaning captain Siwan Lillicrap moves over to the blindside flank and Alisha Butchers shifting to openside flanker. Robyn Wilkins and Ffion Lewis, who sealed Wales' win last time out with a 76th-minute try, are the starting half-backs as Elinor Snowsill and Keira Bevan are named on the bench.
Read more: The best pictures from Wales' thrilling Six Nations win over Scotland after another dramatic finale
On his team selection, Cunningham said: "These players are all deserving of their places, whether they are starting or on the bench. Every player has a key role to play, as we saw against Ireland and Scotland. We are proud of the way we came back to win both our first two games but we must start better and get our penalty count down. They are two of our work-ons plus we need to convert any scoring opportunities.
"The players train and play with and against the England players week in, week out so while we respect the side, there is familiarity, not fear. We are looking forward to playing at Gloucester. Ten of our matchday squad are Gloucester-Hartpury players and it will be fantastic to play in front of a huge crowd there which will hopefully include some Welsh voices too."
Cunningham added: "We are excited by this big challenge against the number one team in the world. On average, they are scoring about eight tries a match, so we are in no doubt about the extent of the task. However, we want to compete with the best teams in the world so this is a great opportunity for us to test ourselves and progress."
Meanwhile, England head coach Simon Middleton has made eight changes to the team which thrashed Italy 74-0 last time out. The Red Roses boss has openly said he is using England's first three gams to rotate the squad before using the final two fixtures against Ireland and France, a likely title decider, to put out his strongest team. Jess Breach is back in the side for the first time since May 2021. Lucy Packer is also set to make her first international start at scrum-half.
Middleton said: "We’re pleased with our performances to date and this weekend provides another opportunity for other players to step up. Wales’ new contracts have galvanised and lifted their group and that’s shown in the nature of their performances and two wins out of two to date. They have looked well organised and have finished strong in both games, that’s testimony to the work Ioan and his staff group have put in and of course the attitude of the players. It’s great to see and makes for a top-class game and a stadium that will be bouncing."
More than 12,000 tickets have been sold for Saturday’s clash.
England: Abby Dow; Jess Breach, Emily Scarratt, 12. Helena Rowland, Sarah McKenna; Zoe Harrison, Lucy Packer; Vickii Cornborough, Lark Davies, Sarah Bern, Poppy Cleall, Abbie Ward, Alex Matthews, Marlie Packer, Sarah Hunter.
Replacements: Connie Powell, Maud Muir, Shaunagh Brown, Rosie Galligan, Vicky Fleetwood, Natasha Hunt, Amber Reed, Ellie Kildunne.
Wales: Kayleigh Powell; Lisa Neumann, Hannah Jones, Kerin Lake, Jasmine Joyce; Robyn Wilkins, Ffion Lewis; Gwenllian Pyrs, Carys Phillips, Donna Rose, Sisilia Tuipulotu, Gwen Crabb, Siwan Lillicrap, Alisha Butchers, Sioned Harries.
Replacements: Kelsey Jones, Cara Hope, Cerys Hale, Alex Callender, Bethan Lewis, Keira Bevan, Elinor Snowsill, Natalia John.
