Jadon Sancho, Mason Mount, James Maddison and Nathaniel Chalobah have been included in England's squad for Nations League meetings with Croatia and Spain.
Gareth Southgate has put his faith in the four uncapped youngsters, with the likes of Tottenham Hotspur's Dele Alli and Manchester United's Jesse Lingard unavailable through injury.
Ross Barkley and Harry Winks return to the squad after catching the eye at club level while Fabian Delph and Ruben Loftus-Cheek are omitted after struggling for regular playing time.
Exciting Borussia Dortmund 18-year-old Sancho has been selected for this month's fixtures, and so too Mount after shining for Sky Bet Championship side Derby since joining from Chelsea on loan.
Former Norwich player Maddison has been rewarded for his first fine start to life at Leicester, while uncapped Watford midfielder Chalobah is back in the squad after recovering from a long-term knee injury.
Harry Winks, capped once, returns the day after starting for Tottenham against Barcelona in the Champions League, and Ross Barkley's upturn in fortunes at Chelsea means he is in line to win his first cap since the friendly against Australia in May 2016.
Injuries and game-time have led to Southgate's squad changes as much as the form of those called-up.
Alli is out with a hamstring injury, while the England boss has not selected Lingard, Fabian Delph and Adam Lallana given the question marks over their fitness.
Ruben Loftus-Cheek, who has not played for Chelsea since starting for England against Switzerland, has also been left out.
The uncapped duo of Marcus Bettinelli and Alex McCarthy again join up with Southgate's goalkeepers.