Jairo Riedewald will be handed his first Premier League start since for almost two years when Crystal Palace host Brighton tonight.
The Dutchman will fill in for the injured pair Patrick van Aanholt and Jeffrey Schlupp, with Palace refusing to place a timescale on either's recovery.
Riedewald, who replaced Schlupp (hip) at half-time against Watford, has not started a top-flight game since a 1-0 defeat to Tottenham in February 2018.
The versatile defender did not play a single minute in the League last season.
Palace boss Roy Hodgson said he may be without one or two more first-team players against Brighton, but would not reveal their identity.
"Those two [Schlupp and Van Aanholt] won’t be available," said Hodgson. "Joel Ward is of course not available.
"Certainly those [are sidelined]. Unfortunately there are one or two others who might get added but I’m not willing to discuss that now."
Mamadou Sakho remains suspended following his red card against Bournemouth, while Gary Cahill and Scott Dann have both been managing problems in recent weeks.
Predicted Crystal Palace XI (4-3-3): Guaita; Kelly, Tomkins, Cahill, Riedewald; Milivojevic, Kouyate, McArthur; Townsend, Zaha, Ayew.
