The Department of Health has been notified of 2,966 new cases of Covid-19.
It is the highest number of cases reported since January of this year, when major restrictions were in place due to the third wave of the virus.
As of this morning there are 470 patients in hospital with Covid-19, down 11 from yesterday.
Of these, 92 people are being treated in ICU, down five on yesterday's figures.
Meanwhile, walk-in and appointment-only vaccination clinics will be open across the country this weekend for people aged 12 and over to receive their first or second dose of the Covid-19 vaccine.
The HSE said that those who received their first dose of the AstraZeneca vaccine, can choose to get an mRNA Pfizer or Moderna vaccine as their second dose.
Children aged 12 to 15 years must attend the centres with their parent or guardian.
However, the HSE said that the walk-in centres are not for booster vaccines, which will begin next week for those over 60 years.
Chief Medical Officer Tony Holohan said yesterday's figures of 2,549 Covid-19 cases represent a high number of cases across the entire population, with the highest incidence among five to 12-year-olds.
"While the Covid-19 vaccines give high protection against severe illness, hospitalisation and death, the way to break transmission is by following all aspects of the public health advice," he said.
Dr Holohan added that people can enjoy Halloween activities safely by taking some simple precautions.
"If you are having visitors over, provide hand sanitiser, open windows and try to ensure people can spread out and keep their distance from one another - avoid crowded parties," Dr Holohan said.
"For trick-or-treaters, give out treats outdoors, if possible. Wash or sanitise hands frequently and before eating or handling treats.
"Neither children nor adults should go trick-or-treating or meet up with others if they have any symptoms of Covid-19, even if symptoms are minor - instead, please isolate and get a test."
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