Leaders in Scotland and Wales have extended lockdown measures announcing small adjustments to come into effect next week.
But both Nicola Sturgeon and Mark Drakeford warned of the danger of the confusing messages coming out of Westminster and warned the public to stay at home this weekend.
Boris Johnson is expected to set out a "roadmap" to loosen the restrictions on Sunday night but officials are worried that some Brits think the lockdown is going to end and have already begun ignoring the regulations.
Mr Johnson spoke with the leaders of the devolved nations on Thursday, ahead of an expected announcement on easing parts of the lockdown in England on Sunday.
Wales' First Minister Mark Drakeford has announced three "modest adjustments" from Monday to restrictions there.
But Ms Sturgeon has said the only change in Scotland would be allowing people to leave their house for exercise more than once a day.
And she urged Scots to respect the rules over the Bank Holiday.
Nicola Sturgeon said at a press conference: "please don't throw away all your good work, don't put yourself or your loved ones at risk".
The First Minister said, on the call with the Prime Minister and leaders of the devolved administrations, there was a "helpful recognition" that the four nations may move at different speeds, should the available data allow it.
The Scottish Government said its data suggests that the R-number is higher in Scotland than the rest of the UK.
Ms Sturgeon said: "The only change that we're considering in the immediate term is the guidance on outdoor exercise, as I mentioned yesterday and I will give you a further update on that over the weekend."
While at a press conference in Wales, the Welsh First Minister Mark Drakeford said lockdown restrictions in the country would continue for a further three weeks, with three "modest adjustments" from Monday.
People will be allowed to exercise more than once a day but they must not travel to do so, with the exercise beginning and ending at home.
The second change is to allow garden centres to reopen if they can observe social distancing rules.
Local authorities will also be able to begin planning how to open libraries and municipal recycling centres.
"These very cautious changes will apply to everyone other than the 120,000 people in the shielding group," Mr Drakeford said.
"We continue to urge people who are over 70, or who have an underlying health condition, or who are pregnant, to continue to take extra care."
Boris Johnson is gearing up to outline a "roadmap" to ease the restrictions and it's understood that the government will drop the "stay at home" message.
Downing Street reiterated that the Prime Minister would exercise "maximum caution" when he announces lockdown changes on Sunday.
Boris Johnson's official spokesman said: "The PM is clear that we are going to adopt an approach of maximum caution.
"I think that is obviously reflected in comments the First Ministers have made in public."
On the devolved administrations possibly announcing different plans from the UK Government, the spokesman added: "The PM has set out on the call (to devolved administration leaders on Thursday) we understand there could be circumstances where there is divergence and when there is evidence that supports it.
"We remain committed to taking a four-nations approach wherever possible."
The Cobra Covid-19 meeting on Sunday, due to take place before Mr Johnson addresses the nation, will involve the devolved leaders, Number 10 confirmed.
Up until now the whole of the UK has moved at the same time.
But the four nations may now take different steps at different times depending on the infection rate.
Mr Drakeford told the Cardiff press conference that the R-value - the number of people the average infected individual would spread the virus to - in Wales is currently around 0.8.
He said the Welsh Government would watch the level "like a hawk" and reimpose any restrictions if it began to rise to previous levels.
Ministers in Wales must review the need for the lockdown requirements and restrictions in the regulations every 21 days.
