Another 40 new cases of coronavirus have been confirmed in the Republic of Ireland today, it has emerged.
This brings the total number to 169 in the Republic and 214 on the island of Ireland, after Northern Ireland's 11 new cases today brought its number to 45.
The HPSC said the new cases in the Republic consisted of 23 men and 17 women.
25 are associated with the east of the country, nine are associated with the west, six are associated with the south.
There have been two confirmed deaths in the Republic of Ireland as of 6pm on March 15.
A statement read: "The HSE is now working to identify any contacts the patients may have had, to provide them with information and advice to prevent further spread.
"The Government has today called on all public houses and bars (including hotel bars) to close from this evening (Sunday 15 March) until at least the 29th March."
Dr. Tony Holohan, Chief Medical Officer, Department of Health said: "In regard to upcoming St. Patrick's Day celebrations, the Government is calling on all members of the public not to organise or participate in any parties in private house or other venues which would put other peoples lives at risk.
"'Everyone is asked to reduce their social contact over this time period.
"'House parties/ COVID parties carry the same risks as being in a pub/club, therefore people should not organise or attend them. The virus is now in our community, it is up to us to limit its spread.
"'Now is the time for action and to heed the public health advice we will continue to provide.'"
Rachel Kenna, Deputy Chief Nurse, Department of Health, said: "Healthcare workers across the service are working under extraordinary conditions, preparing for the potential impact of COVID-19.
"If all citizens work together and comply with social distancing guidelines, and other measures the Government may take in the coming weeks, we will have a stronger response to this virus.
"Help our healthcare workers in their task."
The National Public Health Emergency Team will meet on Monday 15 March to continue its review of Ireland's ongoing preparedness to COVID-19.
Earlier, 11 new cases were confirmed in Northern Ireland, the biggest single-day increase so far.
Northern Ireland's first community transmission cases were confirmed on Friday, with three of the nine cases confirmed on Saturday contracted in the same way.
The NI Department of Health said people with mild symptoms - a new persistent cough and/or a fever - should stay at home and self-isolate for seven days. They will not require testing.
Meanwhile, elderly people in Northern Ireland will be asked to self-isolate for up to four months as part of UK-wide plans to tackle the spread of the coronavirus.
UK Health Secretary Matt Hancock said it is a "very big ask", but described it as a measure which is for their own "self-protection".
On Saturday, Northern Ireland's First Minister Arlene Foster said when schools eventually have to shut in Northern Ireland to help halt the spread of Covid-19, it will be for at least 16 weeks.
Deputy first minister Michelle O'Neill repeated her call for Northern Ireland schools to shut immediately, in line with the Republic of Ireland.