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Manchester Evening News
Manchester Evening News
National
Fionnula Hainey

Coronavirus immunity may only last a few months, new study suggests

Coronavirus immunity in recovered patients might only last for a few months, according to a new study.

The study, conducted by King’s College London, suggests that immunity antibodies fall significantly in the first three months after infection.

That would mean patients are susceptible to getting Covid-19 year after year – similar to the common cold.

The research, which has not yet been peer-reviewed, is believed to be the first longitudinal study of its kind.

Researchers looked into the immune response of 90 coronavirus patients and healthcare workers at Guy’s and St Thomas’ NHS Trust in London.

Analysis showed that a "potent" level of antibodies could be found in 60 per cent of the patients at the peak of their illness.

But only 17 per cent sustained that same level of potency three months later, according to blood tests.

In some cases, antibodies had depleted entirely in that time, the research showed.

The report states that its findings have “important implications when considering widespread (antibody) testing, (antibody) protection against re-infection with (Covid 19) and the durability of vaccine protection.”

It added: “Further studies using sequential samples from these individuals is required to fully determine the longevity of the (antibody) response and studies determining the (antibodies’) threshold for protection from re-infection are needed.”

Experts say the study should be a warning to those assuming they are immune if they have been infected with Covid-19 in the past.

Mala Maini, professor of viral immunology and consultant physician at University College London, said: “This study does reinforce the message that we can’t assume someone who has had Covid-19 can’t get it again just because they initially became antibody-positive.

“It also means a negative antibody test now can’t exclude you having had Covid-19 a few months ago.

“And it suggests vaccines will need to be better at inducing high levels of longer-lasting antibodies than the natural infection, or that doses may need to be repeated to maintain immunity.”

Virologist professor Keith Neal told BBC Breakfast: “It’s not unexpected that antibody levels fall and then the people who had milder illness and therefore mounted a decent immune response were the ones who lost their antibodies most.

“I think that time will tell, currently, as far as I’m aware, nobody has caught Covid-19 twice badly, lots of reports of positives tests, negative-positive and that’s a failure of testing.

“We won’t really know how effective immunity is until we see possible reinfections and we haven’t seen that yet.”

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