Hubei will lift its lockdown at midnight ending two months of isolation, Chinese authorities have confirmed.
The region, which was the centre of the COVID-19 outbreak, was placed on total lockdown earlier this year in a desperate attempt to get the disease under control.
The draconian restrictions saw residents forced to stay indoors while people were banned from entering or leaving the crisis-hit region.
People who are cleared will be able to leave the province after midnight on Tuesday.
However, restrictions on the city of Wuhan will remain until 8 April.
Wuhan residents will soon be allowed to leave with a health tracking code, a QR code, which will have an individual's health status linked to it.
In other parts of the country, authorities have continued to impose tougher screening and quarantine and have diverted international flights from Beijing to other Chinese cities.
However, the risk from overseas infections appears to be on the rise, prompting tougher screening and quarantine measures in major cities such as the capital Beijing.
China had 78 new cases on Monday, a two-fold increase from Sunday.
Of the new cases, 74 were imported infections, up from 39 imported cases a day earlier.
The Chinese capital Beijing was the hardest-hit, with a record 31 new imported cases, followed by southern Guangdong province with 14 and the financial hub of Shanghai with nine.
The total number of imported cases stood at 427 as of Monday.
Only four new cases were local transmissions.
One was in Wuhan which had not reported a new infection in five days.
